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Volume 23 Supplement 3

Selected articles from the International Conference on Intelligent Biology and Medicine (ICIBM 2021): bioinformatics

Research

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. Supplement Editors were not involved in the peer review of any article that they co-authored. The Supplement Editors declare that they have no other competing interests.

Philadelphia, PA, USA8-10 August 2021

Conference website

Edited by Xinghua Shi, Li Shen, Yan Guo, Wei Zhang, Zhongming Zhao and Kai Wang.

  1. Although both copy number variations (CNVs) and single nucleotide variations (SNVs) detected by single-cell RNA sequencing (scRNA-seq) are used to study intratumor heterogeneity and detect clonal groups, a sof...

    Authors: Jeerthi Kannan, Liza Mathews, Zhijie Wu, Neal S. Young and Shouguo Gao
    Citation: BMC Bioinformatics 2022 23(Suppl 3):98
    Content type: Methodology Published on:

  2. With the development of noninvasive imaging technology, collecting different imaging measurements of the same brain has become more and more easy. These multimodal imaging data carry complementary information ...

    Authors: Jin Zhang, Huiai Wang, Ying Zhao, Lei Guo and Lei Du
    Citation: BMC Bioinformatics 2022 23(Suppl 3):128
    Content type: Methodology Published on:

  3. Chronic cough affects approximately 10% of adults. The lack of ICD codes for chronic cough makes it challenging to apply supervised learning methods to predict the characteristics of chronic cough patients, th...

    Authors: Wei Shao, Xiao Luo, Zuoyi Zhang, Zhi Han, Vasu Chandrasekaran, Vladimir Turzhitsky, Vishal Bali, Anna R. Roberts, Megan Metzger, Jarod Baker, Carmen La Rosa, Jessica Weaver, Paul Dexter and Kun Huang
    Citation: BMC Bioinformatics 2022 23(Suppl 3):140
    Content type: Research Published on:

  5. The widely spreading coronavirus disease (COVID-19) has three major spreading properties: pathogenic mutations, spatial, and temporal propagation patterns. We know the spread of the virus geographically and te...

    Authors: Inyoung Sung, Sangseon Lee, Minwoo Pak, Yunyol Shin and Sun Kim
    Citation: BMC Bioinformatics 2022 23(Suppl 3):149
    Content type: Research Published on:

  6. As many complex omics data have been generated during the last two decades, dimensionality reduction problem has been a challenging issue in better mining such data. The omics data typically consists of many f...

    Authors: Tapas Bhadra, Saurav Mallik, Neaj Hasan and Zhongming Zhao
    Citation: BMC Bioinformatics 2022 23(Suppl 3):153
    Content type: Research Published on:

  7. Drug discovery is time-consuming and costly. Machine learning, especially deep learning, shows great potential in quantitative structure–activity relationship (QSAR) modeling to accelerate drug discovery proce...

    Authors: Yang Liu, Hansaim Lim and Lei Xie
    Citation: BMC Bioinformatics 2022 23(Suppl 3):158
    Content type: Research Published on:

  9. The eukaryotic genome is capable of producing multiple isoforms from a gene by alternative polyadenylation (APA) during pre-mRNA processing. APA in the 3′-untranslated region (3′-UTR) of mRNA produces transcri...

    Authors: Naima Ahmed Fahmi, Khandakar Tanvir Ahmed, Jae-Woong Chang, Heba Nassereddeen, Deliang Fan, Jeongsik Yong and Wei Zhang
    Citation: BMC Bioinformatics 2022 23(Suppl 3):396
    Content type: Research Published on:

  11. Brain volume has been widely studied in the neuroimaging field, since it is an important and heritable trait associated with brain development, aging and various neurological and psychiatric disorders. Genome-...

    Authors: Hung Mai, Jingxuan Bao, Paul M. Thompson, Dokyoon Kim and Li Shen
    Citation: BMC Bioinformatics 2022 23(Suppl 3):398
    Content type: Research Published on:

  12. Protein histidine phosphorylation (pHis) plays critical roles in prokaryotic signal transduction pathways and various eukaryotic cellular processes. It is estimated to account for 6–10% of the phosphoproteome,...

    Authors: Jian Zhao, Minhui Zhuang, Jingjing Liu, Meng Zhang, Cong Zeng, Bin Jiang, Jing Wu and Xiaofeng Song
    Citation: BMC Bioinformatics 2022 23(Suppl 3):399
    Content type: Methodology Published on:

  13. In Alzheimer’s Diseases (AD) research, multimodal imaging analysis can unveil complementary information from multiple imaging modalities and further our understanding of the disease. One application is to disc...

    Authors: Yixue Feng, Mansu Kim, Xiaohui Yao, Kefei Liu, Qi Long and Li Shen
    Citation: BMC Bioinformatics 2022 23(Suppl 3):402
    Content type: Research Published on:

  15. Age estimation from panoramic radiographs is a fundamental task in forensic sciences. Previous age assessment studies mainly focused on juvenile rather than elderly populations (> 25 years old). Most proposed ...

    Authors: Xuedong Wang, Yanle Liu, Xinyao Miao, Yin Chen, Xiao Cao, Yuchen Zhang, Shuaicheng Li and Qin Zhou
    Citation: BMC Bioinformatics 2022 23(Suppl 3):426
    Content type: Methodology Published on:

    The Correction to this article has been published in BMC Bioinformatics 2022 23:557

  16. Increasing evidence shows that circRNA plays an essential regulatory role in diseases through interactions with disease-related miRNAs. Identifying circRNA-disease associations is of great significance to prec...

    Authors: Lei Deng, Dayun Liu, Yizhan Li, Runqi Wang, Junyi Liu, Jiaxuan Zhang and Hui Liu
    Citation: BMC Bioinformatics 2022 23(Suppl 3):427
    Content type: Research Published on:

  17. In the context of a binary classification problem, the optimal linear combination of continuous predictors can be estimated by maximizing the area under the receiver operating characteristic curve. For ordinal...

    Authors: Priyam Das, Debsurya De, Raju Maiti, Mona Kamal, Katherine A. Hutcheson, Clifton D. Fuller, Bibhas Chakraborty and Christine B. Peterson
    Citation: BMC Bioinformatics 2022 23(Suppl 3):436
    Content type: Software Published on:

  18. RNA secondary structure has broad impact on the fate of RNA metabolism. The reduced stability of secondary structures near the translation initiation site/start codon of the coding region promotes the efficie...

    Authors: Jianan Lin, Yang Chen, Yuping Zhang, Haifan Lin and Zhengqing Ouyang
    Citation: BMC Bioinformatics 2022 23(Suppl 3):559
    Content type: Research Published on:
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