Fig. 2
From: Incorporating functional annotation with bilevel continuous shrinkage for polygenic risk prediction
Comparison of prediction performance in simulation studies with overlapping annotation groups (Settings 6–7), measured by AUC (a) and \({R}^{2}\) (b). Left: Setting 6 with overlapping pattern I, in which IOU is higher among the annotation groups with low heritability contribution. Right: Setting 7 with overlapping pattern II where IOU is higher among the annotation groups with high heritability contribution