A seed expansion-based method to identify essential proteins by integrating protein–protein interaction sub-networks and multiple biological characteristics

Table 2 The effect of biological data

Dataset	Measures	\(score\_initial\)				Wmatrix				All
Dataset	Measures	GO	Gene	Com	Sub	GO	Gene	Com	Sub	All
DIP	SN	0.5467	0.5467	0.5510	0.5313	0.5441	0.5476	0.5656	0.5296	0.5476
	SP	0.8383	0.8383	0.8395	0.8337	0.8375	0.8385	0.8439	0.8332	0.8385
	PPV	0.5012	0.5012	0.5051	0.4870	0.4988	0.5020	0.5185	0.4855	0.5020
	NPV	0.8615	0.8615	0.8628	0.8568	0.8607	0.8618	0.8673	0.8563	0.8618
	F	0.5230	0.5230	0.5270	0.5082	0.5205	0.5238	0.5410	0.5066	0.5238
	ACC	0.7715	0.7715	0.7734	0.7644	0.7703	0.7718	0.7801	0.7636	0.7718
BioGRID	SN	0.5608	0.5641	0.5742	0.5575	0.5633	0.5633	0.5967	0.5575	0.5642
	SP	0.8340	0.8349	0.8376	0.8332	0.8347	0.8347	0.8437	0.8331	0.8350
	PPV	0.4773	0.4801	0.4887	0.4745	0.4794	0.4794	0.5078	0.4747	0.4801
	NPV	0.8754	0.8764	0.8792	0.8745	0.8761	0.8761	0.8856	0.8745	0.8764
	F	0.5157	0.5188	0.5280	0.5126	0.5180	0.5180	0.5486	0.5126	0.5188
	ACC	0.7759	0.7774	0.7816	0.7745	0.7770	0.7770	0.7912	0.7745	0.7774
Fruitfly	SN	0.2880	0.2880	0.2738	0.2982	0.2880	0.2819	0.2535	0.2941	0.2860
	SP	0.9128	0.9128	0.9118	0.9134	0.9128	0.9123	0.9104	0.9132	0.9126
	PPV	0.1825	0.1825	0.1735	0.1889	0.1825	0.1787	0.1607	0.1864	0.1812
	NPV	0.9499	0.9499	0.9489	0.9506	0.9499	0.9495	0.9475	0.9503	0.9498
	F	0.2234	0.2234	0.2124	0.2313	0.2234	0.2187	0.1967	0.2282	0.2219
	ACC	0.8732	0.8732	0.8714	0.8745	0.8732	0.8724	0.8688	0.8740	0.8729

ISSN: 1471-2105