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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Detection of continuous hierarchical heterogeneity by single-cell surface antigen analysis in the prognosis evaluation of acute myeloid leukaemia

Fig. 2

Differentiation trajectory analysis in samples with untypical LSC blast. a Differentiation trajectory inference in SJ11; b Primitive cells emphasized in red with CD38+ phenotype; c Time-series heatmap of the reported panel in which mature blasts express CD11b+CD45high (blue arrow); d and g pSTAT3 and pAkt in primitive clones showed slightly unregulated responses to G-CSF and SCF; e overall increase of pSTAT5 expression after G-CSF induction; f, h pAkt and pSTAT3 in mature blasts upregulated with the effect of Flt3L and IL-10

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