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Table 3 Comparison of results for 3 cell lines analysed by base accumulation with an ideal moving window

From: Identification of transcription factor high accumulation DNA zones

Cell

line

Input

regions

Moving

window

Method to

search for

HOT zones

Threshold

HOT

zones

HOT

bases

HOT zone

avg length

HOT zone

avg length

standard dev

Conserved

HOT zones

Exclusive

HOT zones

    

Type

Value

      

H1-hESC

81,006

w = 1000

Overlap

4 STD

806

1092

1,434,460

1313.61

545.76

124 (11.4%)

687 (62.9%)

K562

163,444

w = 1000

Overlap

4 STD

2478

1739

1,529,492

879.52

500.84

122 (7.0%)

1,211 (69.6%)

MCF-7

164,108

w = 1000

Overlap

5 STD

1858

1258

1,264,581

1005.23

658.57

121 (9.6%)

835 (66.4%)

  1. For each cell line, we used the overlap method with an over k standard deviations (k STD) threshold to find HOT zones, and then extracted those zones conserved among all the three cell lines, or exclusive of each cell line
  2. avg average, dev deviation