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Table 10 Wrapper methods comparison of predictive performance, number of genes selected and computation time

From: Artificial Intelligence based wrapper for high dimensional feature selection

Dataset

Performance (µ [95% CI])

Predictive performance (RMSE)

Number of genes selected

Computation time (minutes)

StW

AIWRAP-L

StW

AIWRAP-L

StW

AIWRAP-L

TCGA-BLCA

0.79[0.31,1.27]

0.78[0.30,1.26]

4[0,9]

1[0,3]

5.9[3.2,8.6]

12.2[10.1,14.3]

TCGA-CESC

1.00[0.84,1.16]

0.98[0.84,1.13]

10[7, 13]

5[4, 6]

11[7.7,14.2]

14.6[9.9,19.3]

TCGA-ESCA

1.04[0.87,1.20]

1.00[0.85,1.15]

11[5, 17]

8[2, 14]

7.2[4.9,9.5]

27.9[3.6,52.2]

TCGA-HNSC

0.99[0.82,1.16]

0.98[0.81,1.15]

16[12, 20]

6[3, 9]

11.4[8.7,14]

20.3[9.3,31.2]

TCGA-KICH

1.03[0.61,1.46]

0.82[0.39,1.25]

11[9, 13]

6[4, 8]

50.2[24.7,75.7]

10.6[7.5,13.7]

TCGA-KIRP

0.95[0.66,1.24]

0.95[0.65,1.24]

19[18, 20]

15[11, 19]

10.4[8.8,12]

41.1[12.5,69.8]

TCGA-LUAD

1.02[0.93,1.11]

1.02[0.94,1.09]

25[22, 28]

21[16, 26]

11.6[9.1,14.1]

42.3[11.6,72.9]

TCGA-LUSC

0.99[0.91,1.08]

0.99[0.91,1.08]

2[1, 3]

1[0,2]

5.7[4.4,7]

12[8.8,15.2]

TCGA-PAAD

1.26[0.74,1.79]

1.24[0.75,1.73]

22[20, 24]

14[9, 19]

10.8[7.6,14.1]

29[0.6,57.4]

  1. Values in Bold means best results