Table 3 Many-to-many cell–cell interactions (CCIs) detected by only scTensor
From: Sctensor detects many-to-many cell–cell interactions from single cell RNA-sequencing data
Dataset | Signal pathway | Ligand and receptor | Reported |
|---|---|---|---|
FetalKidney [36] | Eph/ephrin | EFNB2–EPHB3 | Yes |
FetalKidney [36] | Eph/ephrin | EFNB2–EPHB4 | No |
FetalKidney [36] | Eph/ephrin | EFNB2–EPHB6 | No |
FetalKidney [36] | Eph/ephrin | EFNA1–EPHA4/7 | No |
FetalKidney [36] | Eph/ephrin | EFNA5–EPHA4/7 | No |
GermlineFemale [25] | Bone morphogenetic protein (BMP) | BMP2–BMPR2 | Yes |
GermlineFemale [25] | Bone morphogenetic protein (BMP) | GDF9–BMPR2 | No |
GermlineFemale [25] | NOTCH | JAG1–NOTCH2 | Yes |
GermlineFemale [25] | NOTCH | JAG1–NOTCH3 | No |
HeadandNeckCancer [54] | Fibroblast growth factor (FGF) | FGF7–FGFR2 | Yes |
Uterus [33] | Insulin-like growth factor (IGF) | Igf1–Igf1r | Yes |
Uterus [33] | Insulin-like growth factor (IGF) | Igf2–Igf1r | No |
Uterus [33] | Pleiotrophin (PTN) | Ptn–Ptprb | Yes |
Uterus [33] | Wingless-related integration site (Wnt) | Rspo3–Lgr5 | Yes |
Uterus [33] | Vascular endothelial growth factor (VEGF) | Vegfa–Kdr | Yes |
Uterus [33] | Vascular endothelial growth factor (VEGF) | Vegfa–Flt1/Nrp1 | No |
VisualCortex [48] | Activin receptor (ACVR) | Inhba–Acvr1b | Yes |
VisualCortex [48] | Activin receptor (ACVR) | Nodal–Acvr1b | No |
VisualCortex [48] | Activin receptor (ACVR) | Nodal/Bmp5/Bmp7–Acvr2a | No |