Fig. 4
From: iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects
DE analysis using iDESC on the two IPF macrophage datasets. a UMAP of nomenclature matched macrophages in the Kaminski and Misharin datasets colored by subject (left) and group (right). b Heatmap of subject-level average expression for the top 10 upregulated and top 10 downregulated genes. c Violin plots demonstrate cell-level contributions to the group fold-change within each subject. Each violin corresponds to one subject and is colored by group