Table 5 Comparisons of experimental results on the glioblastoma dataset
From: Identifying driver pathways based on a parameter-free model and a partheno-genetic algorithm
K | Dendrix | Time(s) | \(r_{pe}(\%)\) |
|---|---|---|---|
2 | CDKN2A TP53 | 94.2 | 100.0 |
3 | RB1 CDKN2B CDK4 | 101.7 | 100.0 |
4 | RB1 CDKN2B CDK4 FUT2 | 104.5 | 75.0 |
5 | RB1 CDKN2B CDK4 FGFR1 CARD8 | 128.1 | 60.0 |
6 | RB1 CDKN2B COL4A1 GML PIH1D1 TSPAN31 | 125.5 | 33.3 |
7 | RB1 CDKN2B CYP27B1 GPR19 PPP1R115A PAN1 TAS2R9 | 125.5 | 28.6 |
8 | RB1 CDKN2B CCNE1 CHEK1 CSNK2A2 NOVA2 PDE6H TSPAN31 | 128.0 | 25.0 |
K | GA | Time(s) | \(r_{pe}(\%)\) |
|---|---|---|---|
2 | CDKN2B CDK4 | 5.5 | 100.0 |
3 | CDKN2B CDK4 RB1 | 6.0 | 100.0 |
4 | CDKN2B CDK4 RB1 ERBB2 | 6.2 | 75.0 |
5 | CDKN2B CDK4 RB1 ERBB2 EMP3 | 6.2 | 60.0 |
6 | CDKN2B CDK4 RB1 ERBB2 CSF1R FCGRT | 6.1 | 50.0 |
7 | CDKN2B CDK4 RB1 ERBB2 FGFR3 NTRK3 ROR2 | 6.3 | 42.9 |
8 | CDKN2B CDK4 RB1 ERBB2 FGFR3 NTRK3 ROR2 SPHK2 | 6.3 | 37.5 |
K | iMCMC | Time(s) | \(r_{pe}(\%)\) |
|---|---|---|---|
2 | CDKN2A CYP27B1 | – | – |
3 | TP53 PTEN MTAP | – | – |
4 | EGFR MDM2 NF1 CHAT | – | – |
K | MOGA | ||
|---|---|---|---|
2 | CDKN2A TP53 | – | – |
3 | CDKN2B CDK4 TP53 | – | – |
K | PGA-MWS | Time(s) | \(r_{pe}(\%)\) |
|---|---|---|---|
2 | CDKN2B CDK4 | 6.0 | 100.0 |
3 | CDKN2A CDK4 TP53 | 11.0 | 100.0 |
4 | CDKN2A CDK4 TP53 NF1 | 24.0 | 75.0 |
5 | CDKN2A CDK4 TP53 COL6A3 NF1 | 39.0 | 60.0 |
6 | CDKN2A CDK4 TP53 COL6A3 NF1 SHH | 42.0 | 50.0 |
7 | CDKN2A CDK4 TP53 COL6A3 NF1 SHH TSPAN31 | 101.0 | 42.9 |
8 | TP53 COL6A3 COL6A2 CDKN2B NF1 RCBTB2 TSPAN31 SHH | 110.0 | 37.5 |
K | CGA-MWS | Time(s) | \(r_{pe}(\%)\) |
|---|---|---|---|
2 | CDKN2B CDK4 | 0.5 | 100.0 |
3 | CDKN2A CDK4 TP53 | 0.5 | 100.0 |
4 | CDKN2B CDK4 RB1 TP53 | 0.7 | 75.0 |
5 | CDKN2B CDK4 RB1 TP53 EGFR | 0.8 | 60.0 |
6 | CDKN2B CDK4 RB1 TP53 EGFR DBC1 | 0.8 | 50.0 |
7 | CDKN2B CDK4 RB1 TP53 EGFR DBC1 NTRK3 | 1.0 | 42.9 |
8 | TP53 CDK4 EGFR FGFR3 CDKN2B RB1 NTRK3 DBC1 | 0.8 | 50.0 |
K | CPGA | Time(s) | \(r_{pe}(\%)\) |
|---|---|---|---|
2 | CDKN2B CDK4 | 14.9 | 100.0 |
3 | CDKN2B CDK4 RB1 | 14.0 | 100.0 |
4 | CDKN2A CDK4 RB1 ERBB2 | 14.7 | 50.0 |
5 | CCNE1 CDK4 ERBB2 CDKN2B RB1 | 22.7 | 60.0 |
6 | CCNE1 CDK4 ERBB2 TP53 CDKN2B RB1 | 25.5 | 66.7 |
7 | CCNE1 CDK4 ERBB2 TP53 FGFR3 CDKN2A RB1 | 26.7 | 71.4 |
8 | TP53 MDM2 EGFR CASP3 PRKDC CDH1 CTNNB1 NUMB | 30.2 | 37.5 |
K | CPGA-SMCMN | Time(s) | \(r_{pe}(\%)\) |
|---|---|---|---|
2 | CDKN2B CDK4 | 30.5 | 100.0 |
3 | CDKN2A TP53 CDK4 | 14.1 | 100.0 |
4 | CDKN2A TP53 CDK4 RB1 | 8.1 | 75.0 |
5 | CDKN2A TP53 CDK4 CCNE1 RB1 | 8.1 | 80.0 |
6 | CDKN2A TP53 CDK4 CCNE1 ERBB2 RB1 | 7.9 | 66.7 |
7 | CDKN2A TP53 CDK4 CCNE1 CASP3 ERBB2 RB1 | 22.2 | 71.4 |
8 | TP53 CDK4 EGFR ERBB2 PDGFRA PIK3R1 PIK3CA CTNNB1 | 15.0 | 87.5 |