Table 5 Comparison of main functions between CRISPRviz, CRISPRStudio and CrisprVi

1

Input files

FASTA

FASTA

GFF, FASTA

2

Detect CRISPRs (DRs/spacers)

MinCED

CRISPRDetect

×

3

Color-symbol system

Glyphicon + color

Diamond + color

Number + strand + color

4

Change color

×

×

√

5

Pairwise alignment of spacers

Needleman-Wunsch algorithm

fasta36 [40]

Modified pairwise alignment

6

Guide tree

UPGMA

UPGMA

UPGMA

7

Show DRs and spacers

√

×

√

8

Show repeats only

√

√

√

9

Show spacers only

√

×

√

10

Align spacers

√

√

√

11

Sort by length

√

×

√

12

Highlight all identical sequences

×

√

√

13

Show information of specific graphics

×

×

√

14

Statistics of DRs/spacers

×

×

√

15

Consensus DR/spacer sequences finding

×

×

√