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Fig. 6 | BMC Bioinformatics

Fig. 6

From: vCOMBAT: a novel tool to create and visualize a computational model of bacterial antibiotic target-binding

Fig. 6

Visualizing antibiotic concentration (An) and complex bound target (AT) and the total bacterial population (BP) over simulated treatment length using the vCOMBAT web-tool. The figure shows a page of the web-based tool displaying antibiotic concentration and complex bound target when using Rifampicin to treat TB with repeated doses daily over 4 days. The results (the graph on the right) are displayed based on model-parameter values provided by users (the panel on the left). In the graph, the x-axis shows the simulated treatment length in hours. The y-axis shows the resulting complex bound target AT (the red area), the total bacterial population BP (the white area), and antibiotic concentration An (the black area, in this case, is covered by AT and BP area) over the treatment time. The user can also choose to display solely AT, BP, or An by adjusting the “Series” link in the upper-left corner of the graph

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BMC Bioinformatics

ISSN: 1471-2105

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