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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Comparative analysis of aneurysm subtypes associated genes based on protein–protein interaction network

Fig. 4

Extensive involvement of the ‘intrinsic’ apoptosis pathway in aneurysm pathogenesis. a The bar plot shows the comprehensive enrichment of the mitochondrial outer membrane permeabilization (MOMP) involved programmed cell death (PCD) pathway in aneurysmal diseases. Genes associated with this enriched pathway are labeled on corresponding bars. b Schematic plot illustrating the classic ‘intrinsic’ apoptosis pathway. c Bubble plot depicting the ‘intrinsic’ apoptosis pathway associated genes with significantly different expression level between human ASH or CA and healthy control. The color of each bubble indicates different change modes of the expression level. DEG, differential expression genes

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