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Table 2 Effects in simulation II

From: Combining heterogeneous subgroups with graph-structured variable selection priors for Cox regression

Protein

\(\beta_{1}\)

\({\varvec{\beta}}_2\)

Akt

2

0

Akt_pS473

2

0

Akt_pT308

2

0

EGFR

0

2

EGFR_pY1068

0

2

EGFR_pY1173

0

2

AMPK_alpha

−1.5

1.5

Annexin.1

1.5

−1.5

GSK3.alpha.beta

−2

−2

GSK3.alpha.beta_pS21_S9

−2

−2

GSK3_pS9

−2

−2

X14.3.3_beta

0

0

X14.3.3_epsilon

0

0

X14.3.3_zeta

0

0

X4E.BP1

0

0

X4E.BP1_pS65

0

0

X4E.BP1_pT37T46

0

0

X4E.BP1_pT70

0

0

X53BP1

0

0

A.Raf_pS299

0

0

  1. Simulated effects in both subgroups. Groups of proteins with the same effect are defined by different phosphorylation sites (or isoforms) of the same protein so that they can learn from each other