From: trioPhaser: using Mendelian inheritance logic to improve genomic phasing of trios
Ashkenazim trio | Han Chinese trio | 50 neuroblastoma trios | |
---|---|---|---|
Genotyped variants | 5,477,879 | 5,040,806 | 5,976,380 sd: 321,208 |
Variants phased by trioPhaser | 4,640,241 (84.7%) | 4,490,039 (89.1%) | 4,469,479 (75.0%) sd: 171,916 |
Variants phased exclusively using Mendelian inheritance logic | 867,181 (18.7%) | 767,992 (17.1%) | 721,415 (16.1%) sd: 54,522 |
Variants phased exclusively by SHAPEIT4 | 458,361 (9.9%) | 417,138 (9.3%) | 420,793 (9.4%) sd: 15,414 |
Run-time (22 CPUs used) | 5.8 h | 5.4 h | 4.4 h |