Fig. 4From: MSA: reproducible mutational signature attribution with confidence based on simulationsPerformance metrics for COSMIC signatures SBS5 and SBS16 with respect to optimisation penalty. SBS5 metrics are derived using point estimates (a) and confidence intervals (b). Similarly, SBS16 metrics are derived using point estimates (c) and confidence intervals (d). Red horizontal line corresponds to the 95% value for each metricBack to article page