Network name | Weighted | Unweighted | Dynamic | Static |
|---|
Entire | | \(\checkmark\) | | \(\checkmark\) |
Induced-Dynamic | | \(\checkmark\) | \(\checkmark\) | |
Induced-Static | | \(\checkmark\) | | \(\checkmark\) |
NetWalk-Dynamic | | \(\checkmark\) | \(\checkmark\) | |
NetWalk-Static | | \(\checkmark\) | | \(\checkmark\) |
NetWalk-Static* | | \(\checkmark\) | | \(\checkmark\) |
wNetWalk-Dynamic | \(\checkmark\) | | \(\checkmark\) | |
wNetWalk-Static* | \(\checkmark\) | | | \(\checkmark\) |
- One of the two entire context-unspecific networks is from HPRD [23], which is quite old, but we use it because many relevant aging-specific subnetworks were already inferred from it in the prior work (see text for details). The other entire context-unspecific network is from BioGRID [24], which we use as the most recent human PPI data (“Data” section). So, when we use HPRD, “Entire” represents the HPRD entire context-unspecific network, and the other seven aging-specific subnetworks are all inferred from HPRD. When we use BioGRID, “Entire” represents the BioGRID entire context-unspecific network, and the other seven aging-specific subnetworks are all inferred from BioGRID. We study HPRD (and its associated aging-specific subnetworks) separately from BioGRID (and its associated aging-specific subnetworks), with the goal of evaluating whether results that we observe for HPRD also hold for the most recent BioGRID data
