Fig. 9
From: EFMlrs: a Python package for elementary flux mode enumeration via lexicographic reverse search
The three Figures show different visualizations of EFMs that belong to the 15,360 identified highest yield EFMs of the sub-model \(sm_8\) of JCVI-syn3A [31]. Each EFM consists of 275 reactions in total. a and b show excerpts of the pathways of EFM 1 and EFM 9 respectively EFM 2 where the respective EFMs only differ in two reactions from each other. Shared reactions are in dark blue whereas individual reactions are in the same color as the EFMs’ name, e.g. in a the reaction GLUTRS_Gln is the shared reaction, reaction GLNTRAT belongs to EFM 1 and GLNTRAT2 belongs to EFM 9. c is a heat map of the top 25 highest yield EFMs, showing the number of reactions in which the EFMs differ from each other. Since EFM 1 differs from EFM 2, respectively EFM 9, in two reactions, consequently EFM 2 and EFM 9 differ in 4 reactions, indicated in the heat map by the number as well as a darker shade of blue. The darker the shade of blue, the greater the similarity between 2 EFMs