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Fig. 1 | BMC Bioinformatics

Fig. 1

From: EFMlrs: a Python package for elementary flux mode enumeration via lexicographic reverse search

Fig. 1

Iteration step of the DDM method visualizing the generation of a new set of extreme rays. a shows a cone with the rays \(e_1\) to \(e_5\). b shows the creation of a new set of extreme rays (\(e_6\) and \(e_7\)) through hyperplane intersection and the pairwise combination of adjacent rays e.g. \(e_5\) and \(e_1\) result in the new extreme ray \(e_6\), \(e_4\) and \(e_3\) in \(e_7\). Other combinations e.g \(e_5\) and \(e_2\) are super-sets of \(e_6\) and \(e_7\) and do not result in new extreme rays. c shows the final cone with all redundant rays removed thus it only consists of the actual EFMs \(e_4\), \(e_5\), \(e_6\) and \(e_7\)

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