Spatial rank-based multifactor dimensionality reduction to detect gene–gene interactions for multivariate phenotypes

Table 4 Hit ratios of MR-MDR according to the presence or absence of outliers (r = 0.25, n = 200)

	Heritability	MR-MDR			Multi-CMDR			Multi-QMDR_FPC
	Heritability	WO	W	Diff	WO	W	Diff	WO	W	Diff
Bivariate	0.01	0.009	0.006	0.003	0.006	0.006	0	0.009	0.007	0.002
Normal	0.025	0.006	0.006	0	0.007	0.006	0.001	0.014	0.013	0.001
	0.05	0.041	0.033	0.008	0.039	0.034	0.005	0.036	0.018	0.018
	0.1	0.131	0.09	0.041	0.142	0.092	0.05	0.143	0.038	0.105
	0.2	0.452	0.364	0.088	0.465	0.375	0.09	0.489	0.121	0.368
	0.3	0.693	0.604	0.089	0.711	0.593	0.118	0.727	0.251	0.476
	0.4	0.865	0.781	0.084	0.873	0.79	0.083	0.883	0.353	0.53
Bivariate	0.01	0.35	0.26	0.09	0.135	0.096	0.039	0.094	0.072	0.022
Gamma	0.025	0.733	0.609	0.124	0.468	0.355	0.113	0.347	0.276	0.071
	0.05	0.776	0.707	0.069	0.661	0.494	0.167	0.606	0.446	0.16
	0.1	0.982	0.947	0.035	0.945	0.748	0.197	0.917	0.692	0.225
	0.2	0.999	0.992	0.007	0.994	0.934	0.06	0.993	0.82	0.173
	0.3	1	1	0	1	0.989	0.011	0.999	0.929	0.07
	0.4	1	1	0	1	0.999	0.001	0.999	0.974	0.025

W/O hit ratio for the data without outlier, W/ hit ratio for the data with outlier, Diff W/O – W, Multi-QMDR_FPC multi-QMDR using first principal component

ISSN: 1471-2105