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Table 2 Top fifteen predicted interactions between pairs of pVOGs with annotated functions

From: Finding functional associations between prokaryotic virus orthologous groups: a proof of concept

pVOG A

pVOG B

P (interaction)

Annotation A

Annotation B

VOG5511

VOG6633

0.996

Tail fiber protein

Putative tail protein

VOG1215

VOG4545

0.996

Minor tail protein

Tape measure protein

VOG0796

VOG5106

0.996

Terminase small subunit

Phage terminase large subunit

VOG0205

VOG4586

0.996

Putative head taill joining protein

Major tail protein

VOG4553

VOG4773

0.994

Major capsid protein

Capsid portal protein Q

VOG4604

VOG5027

0.994

Portal protein

Head morphogenesis protein

VOG4565

VOG9941

0.994

Lysozyme

putative dna maturase b

VOG4555

VOG5106

0.994

Scaffolding protein

Phage terminase large subunit

VOG1190

VOG2368

0.994

Portal protein

Ribonucleoside triphosphate reductase, alpha chain

VOG4545

VOG9209

0.994

Tape measure protein

Minor tail protein L

VOG4545

VOG4599

0.994

Tape measure protein

Minor structural protein

VOG0641

VOG4763

0.994

Holin

Peptidase_S74 protein

VOG0641

VOG4763

0.994

Holin

Minor structural protein

VOG0692

VOG0796

0.994

Minor capsid protein

Terminase small subunit

VOG4811

VOG6163

0.994

Tape measure

Putative tape measure protein

  1. P (interaction) represents the mean predicted probability of a pVOG pair to interact from 500 individual classifiers (decision trees) in the Random Forest. The full list is provided in Additional file 6