Centrality of drug targets in protein networks

BMC Bioinformatics

Table 7 Correlation between enrichment in citations and probability of differences in centrality metrics between Phase4 targets and all targets class (not corrected for multiple testing)

Network	String 0.7			String 0.9			String 0.5			Biogrid			HumanNet XN			Reactome			InBioMap
Network	Shortest path	Degree	Topol. coeff	Shortest path	Degree	Topol. coeff	Shortest path	Degree	Topol. coeff	Shortest path	Degree	Topol. coeff	Shortest path	Degree	Topol. coeff	Shortest path	Degree	Topol. coeff	Shortest path	Degree	Topol. coeff
Adjusted R	0.30	0.30	0.50	− 0.02	− 0.09	− 0.05	0.58	0.38	0.69	− 0.11	0.34	0.54	− 0.06	0.15	0.004	− 0.24	− 0.23	0.06	− 0.20	0.26	− 0.16
P	0.15	0.15	0.07	0.40	0.49	0.43	0.05	0.11	0.03	0.51	0.13	0.06	0.46	0.24	0.37	0.90	0.81	0.65	0.69	0.17	0.61

ISSN: 1471-2105