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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Origins and characterization of variants shared between databases of somatic and germline human mutations

Fig. 1

Similarities in the distribution of somatic and germline variants. a Histogram of Forbes coefficients across somatic samples. Virtually all somatic samples in TCGA have several-fold more variants shared with the germline database than expected by independence. b Mutation rates across nucleotide contexts are correlated between the somatic and germline settings. The set of all heptamers has been split by GC content and color-coded by alternate allele to show correlation structure. Heptamers involving a CpG- > T mutation are omitted from this plot for better visualization of all other heptamers

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BMC Bioinformatics

ISSN: 1471-2105

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