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Table 4 AUC of the evaluated CNV callers on the TCGA AML dataset

From: CNV Radar: an improved method for somatic copy number alteration characterization in oncology

Caller

AUC (gain)

AUC (loss)

CNV Radar

0.83

0.96

CNVkit

0.79

0.80

CoNIFER_FCSVD0

0.43

0.10

CoNIFER_FCSVD1

0.08

0.02

CoNIFER_FCSVD2

0.05

0.03

CoNIFER_FCSVD3

0.04

0.03

CopywriteR

0.79

0.29

ExomeDepth

0.14

0.10

  1. AUC area under the receiver operating characteristic curve; CNV copy number variation; TCGA The Cancer Genome Atlas; AML acute myeloid leukemia; Radar Rapid aberration detection and reporting; CoNIFER copy number inference from exome reads