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Table 3 AUC of the evaluated CNV callers on the MMRF CoMMpass WGS dataset

From: CNV Radar: an improved method for somatic copy number alteration characterization in oncology

CNV Caller

AUC (gain)

AUC (loss)

CNV Radar

0.94

0.90

CNVkit

0.93

0.65

CoNIFER – FCSVD0

0.45

0.59

CoNIFER – FCSVD1

0.23

0.45

CoNIFER – FCSVD2

0.11

0.37

CoNIFER – FCSVD3

0.08

0.28

CopywriteR

0.25

0.01

ExomeDepth

0.05

0.35

  1. AUC area under the receiver operating characteristic curve; CNV copy number variation; MMRF Multiple Myeloma Research Foundation; WGS whole genome sequencing; Radar rapid aberration detection and reporting; CoNIFER copy number inference from exome reads
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BMC Bioinformatics

ISSN: 1471-2105

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