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Fig. 10 | BMC Bioinformatics

Fig. 10

From: Visually guided classification trees for analyzing chronic patients

Fig. 10

Classification tree considering age, gender, and diagnosis and drug codes for CRGs 1000-5192-5424-6144-7071. The LDA plot shows that samples in CRGs 1000 and 5192 are separated from the rest (see the right part of the plot). Note that these CRGs are associated with the leaf nodes on the left branch of the tree. As expected, the absence of diagnosis codes related to DM (‘250’) and EH (‘401’), together with the absence of drug codes related to DM (‘A10BA’) and EH (‘C09AA’) leads to healthy patients, which is consistent with domain knowledge. The presence of the diagnosis code ‘401’ or the presence of the drug code ‘C09AA’ identifies patients in CRG-5192. Also, in accordance with previously designed trees, the presence of diagnosis code ‘496’ or drug code ‘N05AL’ helps us to identify the patients belonging to CRG-7071. Since this is the tree that considers more health statuses, the relationships among features and CRGs may be more difficult to interpret, and to verify whether they agree with current clinical knowledge

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