Fig. 2

Outputs of MIENTURNET web tool with the example list of genes as input. a Table of results from miRNA-target enrichment analysis (top); bar plot representing each miRNA resulting from the enrichment along with the number of its target genes (bottom). The color of the bars represent the adjusted p-values (FDR). b Visualization of miRNA-target interaction network where blue circles refer to miRNAs, while yellow circles refer to their target genes. c Table of network topological properties (top); network degree plots for target genes (bottom-left) and for miRNAs (bottom-middle); and nodes degree distribution shown on double logarithmic axis (log-log plot), in which the straight line corresponds to the power-law fit (bottom-right). d Dot plot of functional enrichment analysis for target genes of selected miRNAs resulting from the enrichment analysis. The Y-axis reports the annotation categories (e.g. KEGG pathways) and the X-axis reports the selected miRNAs. The color of the dots represent the adjusted p-values (FDR), whereas the size of the dots represents gene ratio (i.e. the number of miRNA targets found enriched in each category over the number of total genes associated to that category)