Fig. 2

VOLARE screenshot: Network at the top, two detailed regression plots below, and top table at the bottom. Buttons add labels to the nodes, synchronize the table with the network, or synchronize the network with the table. The top table can be filtered by typing text to match. The table contains one row for each relationship, listing the analytes that comprise the relationship, the test statistic (in this case F), an adjusted p-value (pAdj), and a small plot illustrating the fitted model (microplot, abbreviated mPlot). Clicking on a microplot generates the corresponding detailed graph. The key = label above each detailed plot references the corresponding row in the top table. In each detailed plot, the x-axis represents the immune cell population (measured in percent of parent population) while the y-axis represents the microbial taxa (measured in relative abundance, in the range from 0 to 1). Each point represents the values for one sample from one person. Points are color coded to represent the cohort to which the corresponding person belongs. Lines represent the fitted regression model for each cohort. The closer the points are to the line, the better the model