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Table 5 Summary of results for proteins identified in the global controllability analysis

From: A dual controllability analysis of influenza virus-host protein-protein interaction networks for antiviral drug target discovery

Quality

Frequency in Global Protein Set

Driver protein

100%

IAV interacting protein

100%

Identified in robust protein set

8%

Validated in at least one siRNA screen

21%

Cell infection – functional enrichment

25%

mRNA processing – functional enrichment

17%

Interferon regulating gene

83%