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Table 4 Proportions of essential leading cascade reactions according to the cascade number in the reaction-centric metabolic networks

From: Identification of critical connectors in the directed reaction-centric graphs of microbial metabolic networks

Reaction graphs from

Cascade number

r

0

1

2

3

4

5

6

>  7

Total

E. coli (iJO1366)

13.4% (94/697)

29.1% (37/127)

30.7% (8/26)

47.6% (10/21)

15.3% (2/13)

25.0% (1/4)

50.0% (1/2)

100% (4/4)

17.5% (157/894)

0.68

B. subtilis (iYO844)

22.4% (101/450)

32.2% (19/59)

50.0% (7/14)

83.3% (5/6)

100% (3/3)

ND

50.0% (1/2)

57.1% (4/7)

25.8% (140/541)

0.43

G. metallireducens (iAF987)

28.7% (136/473)

65.1% (56/86)

50.0% (13/26)

61.5% (16/26)

54.5% (6/11)

66.6% (2/3)

100% (4/4)

100% (1/1)

37.1% (234/630)

0.86

K. pneumoniae (iYL1228)

10.4% (65/620)

28.5% (30/105)

19.3% (6/31)

60.0% (6/10)

41.1% (7/17)

66.6% (2/3)

100% (1/1)

33.3% (2/6)

15.0% (119/793)

0.63

S. cerevisiae (iMM904)

10.3% (54/520)

14.4% (11/76)

37.5% (9/24)

41.6% (5/12)

33.3% (2/6)

50.0% (1/2)

50.0% (1/2)

33.3% (1/3)

13.0% (84/645)

0.72

  1. Each cell denotes % essential leading cascade reactions (No. essential leading cascade reactions / No. of total leading cascade reactions). Last column indicates correlation coefficient (r) between cascade numbers and % essentialities