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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets

Fig. 2

Nucleotide-conversion aware read mapping: a Evaluation of nucleotide-conversion aware scoring vs naïve scoring during read mapping: Median error [%] of true vs recovered nucleotide-conversions for simulated data with 100 bp read length and increasing nucleotide-conversion rates at 100x coverage. b Number of reads correctly assigned to their 3′ interval of origin for typically encountered nucleotide-conversion rates of 0.0, 2.4 and 7.0% as well as excessive conversion rates of 15, 30 and 60%. c Percentages of retained reads and linear regression with 95% CI bands after mapping 21 mouse ES cell pulse-chase time course samples with increasing nucleotide-conversion content for standard mapping and DUNK

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