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Fig. 3 | BMC Bioinformatics

Fig. 3

From: HOME: a histogram based machine learning approach for effective identification of differentially methylated regions

Fig. 3

Quality assessment of CG-DMRs predicted in mammalian WGBS data by HOME, DSS and Metilene. (a) Browser representation showing the quality and boundary accuracy of predicted CG context DMRs for the PV specific gene Syt2. (b) Heatmap of methylation level difference for all predicted DMRs by HOME, DSS and Metilene. The DMRs are sorted by length. The bin size is 200 bp for all heatmaps. (c) Mean and standard deviation of absolute methylation difference for all predicted CG DMRs for 5 CGs upstream and downstream of the DMR start (left) and stop (right) marked as 0, respectively. (d) Heatmap of methylation level difference for uniquely predicted DMRs by HOME, DSS and Metilene

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