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Table 5 Number of KEGG gene sets and GO terms enriched by the top 300 DE genes identified by each tool under an FDR threshold of 0.05

From: Comparative analysis of differential gene expression analysis tools for single-cell RNA sequencing data

Methods

KEGG

GO Term

EMDomics

53

19

MAST

10

5

D3E

49

10

SCDE

21

9

Monocle2

42

24

SINCERA

39

16

scDD

26

1

DESeq2

39

19

edgeR

39

17

SigEMD

23

15

DEsingle

41

21

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BMC Bioinformatics

ISSN: 1471-2105

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