Comparative analysis of differential gene expression analysis tools for single-cell RNA sequencing data

BMC Bioinformatics

Table 3 Number of detected DE genes, and sensitivities of the eleven tools using positive control real data for an adjusted p-value or FDR of 0.05

	Number of detected DE genes	Sensitivity (TP/1000 gold standard)
Monocle2	8674	0.765
EMDomics	8437	0.762
DESeq2	7612	0.695
D3E	8401	0.722
scDD	2638	0.351
MAST	734	0.198
edgeR	4447	0.58
SCDE	2414	0.392
SINCERA	8366	0.73
DEsingle	9031	0.797
SigEMD	3702	0.488

ISSN: 1471-2105