Fig. 4

Free simulation with the single-MFE fitness function (top) and MFE-set fitness (bottom): the x-axis is scaled by square root. The quantities depicted are as follows. The distance of the dominant structure of the population to the target (black curve). The mean energy and mean number of base pairs in the population (the blue and purple curves respectively). The number of degenerate sequences and the number of sequences folding to the dominant structures respectively, each divided by 20 to fit in the picture (the yellow and red curves). Transitions of the dominant structure (step-wise orange curve). This curves goes up one step each time the dominant structure is changed (normalized to end at 50). The degeneracy of the parent of the current dominant structure (gray curve)