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Table 5 Gene Ontology (GO) enrichment analysis result

From: A new insight into underlying disease mechanism through semi-parametric latent differential network model

ID

Functional term

Ontology

Adjust P-value

   

C-RDN

B-RDN

DDN

GO:0016055

Wnt signaling pathway

BP

1.69×10−11

2.96×10−6

0.0022

GO:0198738

cell-cell signaling by wnt

BP

1.69×10−11

2.96×10−6

0.0022

GO:0060828

regulation of canonical Wnt signaling pathway

BP

1.49×10−9

0.0012

0.0027

GO:0060070

canonical Wnt signaling pathway

BP

4.78×10−9

0.0012

0.0027

GO:0030111

regulation of Wnt signaling pathway

BP

6.67×10−9

0.0058

0.0091

GO:0005109

frizzled binding

MF

5.28×10−5

0.0058

0.0091

GO:0007369

gastrulation

BP

0.0024

0.0058

0.0276

GO:0017147

Wnt-protein binding

MF

0.0025

0.0073

0.0286

GO:0060562

epithelial tube morphogenesis

BP

0.0068

0.0073

0.0290

GO:0003002

regionalization

BP

0.0074

0.0080

0.0331

GO:0035239

tube morphogenesis

BP

0.0082

0.0090

0.0332

GO:0001503

ossification

BP

0.0093

0.0131

0.0341

GO:0007389

pattern specification process

BP

0.0113

0.0131

0.0357

GO:0043393

regulation of protein binding

BP

0.0202

0.0175

0.0377

GO:0034329

cell junction assembly

BP

0.0205

0.0178

0.0382

GO:0030877

beta-catenin destruction complex

CC

0.0223

0.0377

0.0382

GO:0045216

cell-cell junction organization

BP

0.0229

0.0409

0.0402

GO:0034330

cell junction organization

BP

0.0259

0.0411

0.0408

GO:0071496

cellular response to external stimulus

BP

0.0281

0.0411

0.0418

GO:0071214

cellular response to abiotic stimulus

BP

0.0290

0.0421

0.0448

GO:0104004

cellular response to environmental stimulus

BP

0.0290

0.0450

0.0453

GO:0051098

regulation of binding

BP

0.0330

0.0474

0.0478

GO:0045992

negative regulation of embryonic development

BP

0.0341

0.0479

0.0495

GO:1903829

positive regulation of cellular protein localization

BP

0.0397

0.0489

0.0495

GO:1901990

regulation of mitotic cell cycle phase transition

BP

0.0409

0.0489

0.0498

  1. BP: biological process; MF: molecular function; CC: cellular component