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Table 2 P-values or P(k) of each pathway under different methods

From: Probabilistic prioritization of candidate pathway association with pathway score

 

p53

estrogen

Jak-STAT

mTOR

oocyte meiosis

taste transduction

Size

68 (290)

99 (838)

158 (1039)

60 (433)

124 (499)

83 (247)

Bayesian

0.717

0.736

0.895

0.722

0.611

0.554

Logistic (sum)

0.386

0.447

0.009

0.006

0.038

0.006

GSEA

0.264

0.134

0.306

0.571

<1e-4

0.228

SPIA

0.195

0.396

0.266

0.956

0.222

0.983

Global

<1e-21

<1e-17

<1e-22

<1e-23

<1e-16

<1e-15

ORA

0.036

0.101

0.275

0.469

0.086

0.083

Fisher’s

<1e-214

0

<1e-311

<1e-314

0

<1e-67

  1. Numbers underlined and in boldface indicate the most influential pathway (top-ranked) under each test; while numbers in boldface represent the least influential pathway. The second row lists the number of genes in each pathway, where the number in parentheses includes the genes in sub-pathway. The p-values under Global and Fisher’s are asymptotic approximates