Fig. 6

Differentially Expressed Genes Matched to AF/LO Subnetworks in a Tiled View. Shown are all 60 AF/LO subnetworks containing at least one gene from the list of differentially expressed genes [37]. The homology observations are included in the subnetworks without genes that are not from the list of differentially expressed genes. The 151 differentially expressed genes are marked by a halo. Genes with experimental ageing relevance evidence are labelled with their gene symbol. The qualitative lifespan effect is encoded in the LO node and edge colour, according to the colour scheme below. Network size: 952 nodes, 898 edges; Layout calculation: FMMM algorithm with standard parameters; Color scheme: AF - gene, AF - compound, AF - other factor, LO - increased lifespan, LO - decreased lifespan, LO - unchanged lifespan, observation - homology analysis, differentially expressed gene (gene of interest)