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Fig. 2 | BMC Bioinformatics

Fig. 2

From: XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

Fig. 2

Mapping of mouse DNA and RNA to the human reference genome. a: Pair-wise comparison of the number of sequence reads per exon from mouse WGS (BALB_Cj versus C57BL_6NJ) mapped to a human reference. b: Number of reads (log10) that originate from mouse that mapped to the human reference, sorted by reads count; per exon (left panel) and per gene (right). c: Number of mouse reads from WGS that mapped to the human gene PTEN. d Number of mouse reads from WGS that mapped to the human gene BCL9. e: Comparison for read count of BALB_Cj RNAseq and WGS, both mapped to a human reference. Read count is corrected for exon length. f: Comparison for exon read count of WGS and WES of mouse DNA, both mapped to a human reference. WES on mouse DNA was performed with a human-specific enrichment kit

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