Fig. 5
Comparison of the three networks used to compute the CN. The first row shows the distribution of significant wTO values (padj-value <0.01). Note that the wTO range of the second network is larger than of the other two networks. The second row show the wTO network for each method. The third and forth row refer to the CN. Note that now the distribution of the wTO values does not include the wTO values close to zero, and retains only values that show a high correlation between the TFs. In the histograms, the presence of negative wTO values is visible, indicating that there are TFs that downregulate other genes