From: Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios
Genome Denmark | |||||||||
---|---|---|---|---|---|---|---|---|---|
Allele | Northern Ireland | Sweden (South) | Sweden (North) | Germany | England (North) | Basque Country | Scotland Orkney | Polysolver | Optitype |
A*02:01 | 0.27 | 0.26 | 0.24 | 0.28 | 0.29 | 0.27 | NA | [#1] 0.26 | [#1] 0.24 |
A*01:01 | 0.20 | 0.09 | 0.08 | 0.15 | 0.21 | NA | NA | [#2] 0.21 | [#2] 0.22 |
A*03:01 | 0.14 | 0.25 | 0.31 | 0.15 | 0.14 | NA | NA | [#3] 0.17 | [#3] 0.17 |
A*24:02 | NA | 0.13 | 0.21 | 0.09 | 0.07 | NA | NA | [#4] 0.09 | [#5] 0.04 |
A*11:01 | 0.08 | 0.06 | 0.01 | 0.06 | 0.07 | NA | NA | [#5] 0.04 | < 0.04 |
A*23:01 | 0.01 | NA | NA | 0.023 | 0.02 | 0.02 | NA | < 0.045 | [#4] 0.05 |
B*07:02 | 0.17 | 0.19 | 0.19 | 0.12 | 0.15 | NA | NA | [#1] 0.18 | [#1] 0.18 |
B*07:05 | 10−3 | NA | NA | 4 × 10−3 | 3 × 10−3 | NA | NA | [#2] 0.15 | < 0.06 |
B*15:01 | 0.04 | 0.14 | 0.15 | 0.06 | 0.06 | NA | NA | [#3] 0.07 | [#4] 0.09 |
B*44:02 | 0.13 | 0.10 | 0.03 | 0.07 | 0.10 | NA | 0.26 | [#4] 0.07 | [#3] 0.09 |
B*40:01 | 0.05 | 0.10 | 0.14 | 0.05 | 0.06 | NA | 0.06 | [#5] 0.06 | [#5] 0.06 |
B*08:01 | 0.16 | 0.07 | 0.05 | 0.09 | 0.15 | NA | 0.17 | < 0.06 | [#2] 0.13 |
C*07:01 | NA | NS | NS | 0.15 | 0.19 | NA | NA | [#1] 0.19 | [#1]0.2 |
C*07:02 | 0.19 | NS | NS | 0.13 | 0.16 | NA | NA | [#2] 0.18 | [#2] 0.17 |
C*06:02 | 0.09 | NS | NS | 0.1 | 0.09 | 0.03 | 0.07 | [#3] 0.11 | [#4] 0.1 |
C*03:03 | 0.05 | NS | NS | 0.05 | 0.06 | 0.07 | 0.09 | < 0.08 | [#3] 0.11 |
C*03:04 | 0.06 | NS | NS | 0.07 | 0.08 | 0.05 | 0.05 | [#4] 0.09 | [#5] < 0.09 |
C*05:01 | 0.13 | NS | NS | 0.06 | 0.10 | 0.14 | 5 × 10−3 | [#5] 0.08 | 0.09 |