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Table 1 Descent Accuracy (DA) for the two typers considered

From: Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

Typer

Overall

HLA-A

HLA-B

HLA-C

Polysolver (4-digit)

0.95

0.95

0.95

0.96

Optitype (4-digit)

0.88

0.95

0.82

0.87

Polysolver (8-digit)

0.64

0.47

0.68

0.77

  1. Optitype at 4-digit resolution performed better than Polysolver having 8-digit resolution. However, when allele reduction is applied Polysolver surpasses the results provided by Optitype on the Genome Denmark cohort
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BMC Bioinformatics

ISSN: 1471-2105

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