Fig. 2From: MERIT reveals the impact of genomic context on sequencing error rate in ultra-deep applicationsEstimated context-specific substitution error rates for polymerase Hi-Fi 2X. a) R1 reads. b) R2 read. c) Γ, the ratio of error rate in R1 over R2. P-values were computed by performing a two-tailed z-test. d) Δ, the difference between their corresponding Phred quality scores. We reduced the depth of paired-end reads to approximately 1,300,000 × through an in silico depth reduction procedure. Results were obtained by averaging over 100 independent samples to establish error bars which indicate one standard deviation from the averageBack to article page