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Fig. 6 | BMC Bioinformatics

Fig. 6

From: Spatial registration of neuron morphologies based on maximization of volume overlap

Fig. 6

Comparison of dendritic density profiles generated using Reg-MaxS-N and brain altas based method. a Two dimensional projections of morphological densities after registration with Reg-MaxS-N (left columns) and standard brain based registration (right columns). Densities were calcuated for voxels of size 0.25μm. Color indicates the fraction of morphologies that, after registration, had at least one dendrite in the particular voxel. For illustration purposes, densities have been smoothed by a 3D Gaussian kernel with standard deviation of 1.25μm. a Densities for eight LCInt morphologies. A1, A2 and A3 correspond to the principal axes of the standardized LCInt morphology used as initial reference. b Densities for fourteen ALPN morphologies. A4, A5 and A6 correspond to the principal axes of the standardized ALPN morphology used as initial reference. c Densities for twelve AA1 morphologies. A7, A8 and A9 correspond to the principal axes of the standardized AA1 morphology used as initial reference. d Densities for nine AA2 morphologies. A10, A11 and A12 correspond to the principal axes of the standardized AA2 morphology used as initial reference. In all cases, Reg-MaxS-N produced densities very similar to that produced by standard brain based method

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