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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Spatial registration of neuron morphologies based on maximization of volume overlap

Fig. 1

Volume representation of morphologies and spatial dissimilarity profiles at different voxel sizes illustrated using planar morphologies. Top row: Two example planar morphologies with volume representations at different voxel sizes. Circles visualize SWC points and lines their connectivity, with circle sizes indicating the diameter of the points. The two morphologies are identical but are rotated against each other about their centroids. Their discretized volume representations at corresponding voxel sizes are indicated by the filled squares. Bottom row: Variation of spatial dissimilarity between the morphologies at different voxel sizes as one of the morphologies (red morphology in top row) was rotated about its centroid. Dissimilarity was quantified using the spatial non-centric measure (see main text). The actual rotation difference between the morphologies is indicated by the red line. With decreasing voxel size, spatial dissimilarity profiles show increasing number of local minima (green arrows)

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