Fig. 2From: PON-SC – program for identifying steric clashes caused by amino acid substitutionsAn example of a clash between atoms caused by amino acid a substitution. Substitution of Leu98 (white) by Glu (top) in SH2D1A protein (PDB id 1D4W) causes no clashes with the surrounding residues, while substitution with Arg (bottom) causes clashes with Ile84 and Tyr29 (indicated by circles)Back to article page