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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs

Fig. 1

Illustration of the RWRMTN and RWRMDA methods. a Heterogeneous miRNA networks/MiRNA-target networks were constructed using miRNA-target gene interactions. b Homogeneous miRNA networks/MiRNA functional similarity networks were constructed using target genes shared among miRNAs. c Two miRNAs known to be associated with a disease under study are mapped as source/seed nodes in a homogeneous miRNA network. In addition to these two known disease-associated miRNAs, their target genes are also used as source/seed nodes in a heterogeneous miRNA network. d Ranking methods score all nodes in the heterogeneous or homogeneous miRNA network

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BMC Bioinformatics

ISSN: 1471-2105

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