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Table 1 Clonotypes identified with HashClone analysis and IMGT validation

From: HashClone: a new tool to quantify the minimal residual disease in B-cell lymphoma from deep sequencing data

 

Phase A

Phase B

Study

Patient

Clonotype

Clonotype with

Clonotype with

 

(only diagnosis samples)

identified

frequency >100

VDJ homology >80%

Pilot 1

A

1616

12

7

 

B

1703

59

33

 

C

2149

72

44

 

D

870

10

5

 

E

1398

35

21

 

Average value

1547

38

22

Pilot 2

A

96

18

6

 

B

278

72

11

 

E

77

5

0

 

Average value

150

32

6

  1. For each patient of both Pilot studies the total number of identified clonotypes (third column) is reported. The number of clonotypes with a frequency greater than 100 were selected and passed the Phase A are reported in fourth column. Then from the Phase A, clonotypes with a VDJ homology greater than 80% were selected and passed the Phase B (fifth column). The average value are reported in bold
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BMC Bioinformatics

ISSN: 1471-2105

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