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Table 2 Results of MCTS-RNA, antaRNA and MODENA for individual Rfam targets

From: RNA inverse folding using Monte Carlo tree search

Data

MCTS-RNA

antaRNA

MODENA

Rfam

RfamID

N

â„“

Sc

E t

Sc

E t

Sc

E t

RF00001

5S_rRNA

117

83

44/50

196.87

4/50

28.87

0/50

–

RF00002

5_8S_rRNA|

151

127

41/50

166.06

0/50

–

13/50

64.62

RF00003

U1

161

121

5/50

371.86

0/50

–

50/50

84.43

RF00004

U2

193

149

50/50

3.4

50/50

20.04

50/50

130.99

RF00005

tRNA

74

53

50/50

0.15

50/50

0.64

50/50

32.25

RF00006

Vault

89

69

50/50

0.38

50/50

3.65

50/50

37.49

RF00007

U12

154

112

50/50

10.08

19/50

8.19

49/50

76.19

RF00008

Hammerhead_3

54

39

50/50

0.49

50/50

0.33

50/50

28.32

RF00009

RNaseP_nuc

348

293

48/50

84.58

0/50

–

0/50

–

RF00010

RNaseP_bact_a

357

255

0/50

–

0/50

–

0/50

–

RF00011

RNaseP_bact_b

382

286

0/50

–

0/50

–

0/50

–

RF00012

U3

215

176

50/50

5.64

50/50

30.6

50/50

197.66

RF00013

6S

185

137

50/50

31.05

46/50

12.83

50/50

124.12

RF00014

DsrA

87

58

50/50

0.1

44/50

0.78

42/50

40.6

RF00015

U4

140

109

50/50

2.07

22/50

10.59

49/50

62.18

RF00016

SNORD14

129

112

0/50

–

0/50

–

0/50

–

RF00017

SRP_euk_arch4

301

200

49/50

133.19

44/50

56.24

50/50

452.17

RF00018

CsrB

360

311

0/50

–

0/50

–

0/50

–

RF00019

Y_RNA

83

60

50/50

1.51

49/50

1.67

50/50

36.32

RF00020

U5

119

89

0/50

–

0/50

–

0/50

–

RF00021

Spot_42

118

81

50/50

0.26

50/50

0.98

50/50

55.34

RF00022

GcvB

148

115

50/50

1.34

49/50

10.04

50/50

74.6

RF00024

Telomerase-vert

451

346

0/50

–

0/50

–

0/50

–

RF00025

Telomerase-cil

210

173

50/50

4.88

22/50

71.32

50/50

170.58

RF00026

U6

102

97

50/50

1.6

50/50

3.37

50/50

84.66

RF00027

let-7

79

48

50/50

0.19

50/50

0.76

50/50

37.35

RF00028

Intron_gp

344

291

7/50

336.39

0/50

–

0/50

–

RF00029

Intron_gpI

73

54

50/50

2.16

14/50

7.49

50/50

35.46

RF00030

RNase_MRP

340

276

50/50

19.96

31/50

298.74

50/50

414.19

Total

   

1045/1450

 

744/1450

 

953/1450

 
  1. The GC content is controlled to 0.5 and the time limit is set to 10 min. N denotes the length of the target structure. â„“ describes the sum of the number of base pairs and that of free bases in the target structure. For each method, the number of successes in 50 runs is shown as Sc, and E t indicates the average time (in seconds) required to find a compliant sequence. If no compliant sequences are found, it is left blank