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Table 3 Comparison between QuaDMutEx and other methods. For QuaDMutEx, we used default parameter values k=1 and C=1 unless specified otherwise

From: QuaDMutEx: quadratic driver mutation explorer

Method

Genes

Coverage

Excess

Dendrix

   

coverage

score

GBM: Glioblastoma multiforme

 TiMEx

3

0.7857

0.0606

62

 RME

3

0.7857

0.0606

62

 CoMEt

5

0.8452

0.0845

65

 Dendrix

9

0.8571

0.0556

68

 QuaDMutEx (C=0.5)

12

0.9286

0.0769

72

 QuaDMutEx

7

0.8690

0.0822

67

OV: Ovarian Cancer

 TiMEx

2

0.9525

0

301

 RME

5

0.9494

0.1

62

 CoMEt

2

0.9525

0

301

 Dendrix

3

0.9557

0

302

 QuaDMutEx

3

0.9557

0

302

LUNG: Lung Adenocarcinoma

 TiMEx

2

0.5521

0

90

 RME

3

0.6748

0.1273

96

 CoMEt

6

0.6196

0

101

 Dendrix

12

0.6809

0.0270

108

 QuaDMutEx

15

0.8160

0.1053

119

BRCA: Breast Invasive Carcinoma

 TiMEx

3

0.4202

0.1006

289

 RME

3

0.3865

0.0268

290

 CoMEt

3

0.2620

0

202

 Dendrix

29

0.5811

0.09598

402

 QuaDMutEx (C=1.5)

20

0.6109

0.1338

408

 QuaDMutEx

26

0.6342

0.1595

411

  1. Highest result for each dataset indicated in italics