Fig. 2

The workflow of MetaComp. The input data of MetaComp includes meta-omics data (for all analyses) and environmental factors input (only for regression analysis). The analysis procedure in MetaComp consist of three independent parts: multivariate statistics (PCA and cluster analysis), statistical hypothesis tests (two-sample test, multi-sample test and two-group sample test) and regression analysis of environmental factors. The outputs are provided in Excel spreadsheet (k-means clustering results, statistically significance for each feature and regression analysis results) and visualized in diagrams (PCA map, hierarchical clustering dendrogram, bar plot, MDS map, heat-map)